BDBM50299218 8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydroxyphenyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione::CHEMBL566515::Cpd66

SMILES COc1ccccc1-n1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1cc(O)ccc1C

InChI Key InChIKey=JTWMOWRMSZZHDR-UHFFFAOYSA-N

Data  19 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299218   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  0.920nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed